X Chromosome Inactivation: New Hope for Genetic Disorders

April 7, 2025

X chromosome inactivation (XCI) is a remarkable biological process that delicately balances gene expression in female mammals, where two X chromosomes reside, compared to males who have only one.This intricate mechanism ensures that cells do not operate with an excess of gene activity from the X chromosome, helping to prevent the phenotype imbalances seen in conditions such as Fragile X Syndrome and Rett Syndrome.
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